BRAF p.L597V Reference Standard
CBP10241
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索取COA
產品描述
產品數(shù)據庫
| Introduction | |
| Format | Genomic DNA |
| Description | BRAF L597V lies within the protein kinase domain of the Braf protein (UniProt.org). L597V results in activation of Braf as indicated by increased phosphorylation of Mek and Erk in cell culture (PMID: 22798288) and and induces cell proliferation and cell viability in culture (PMID: 29533785). |
| Technical Data | |
| DNA Change | c.1789C>G |
| AA Change | p.L597V |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 33.33% |
| Transcript | ENST00000288602 |
| Cosmic ID | COSM470 |
| Chr position(GRCh37) | chr7:140453146 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |  |
| Storage | 2-8℃ |
| Expiry | 36 months from the date of manufacture |
