ERBB4 WT(NRG1b Dependent)/BaF3
CBP73257
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產品描述
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| I. Introduction | |
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Cell Line Name： |
ERBB4 WT(NRG1b Dependent)/BaF3 |
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Host Cell: |
Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
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Application: |
Anti-proliferation assay and PD assay |
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Freeze Medium: |
90% FBS+10% DMSO |
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Complete Culture Medium: |
RPMI-1640+10%FBS+10ng/ml NRG1-beta1 |
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Mycoplasma Status: |
Negative |
| II. Background | |
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Human HER4 kinase, also known as Erb-B4, Proto-Oncogene-Like Protein C-ErbB-4, and Tyrosine Kinase-Type Cell Surface Receptor HER4, GenBank Accession No. NM_005235, a.a. 708-993, with an N-terminal GST-tag, expressed in a Baculovirus infected Sf9 cell expression system. MW=59.5 kDa. |
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| III. Representative Data | |
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1. ERBB4 WT(NRG1b Dependent)/BaF3
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2. Anti-proliferation assay
Figure 2. Anti-proliferation assay of three reference compounds on the ERBB4 WT(NRG1b Dependent)/BaF3 Stable Cell line. |
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